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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14004 | 1A-116 | Rho | |
1A-116 is a specific inhibitor of Rac1 . | |||
T9356 | (E/Z)-GO289 | Casein Kinase | |
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function... | |||
T9608 | KL201 | Others | |
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1]. | |||
T32401 | KL044 | KL 044,KL-044 | Others |
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway. | |||
T27430 | GR 196429 | GR-196429,GR 196,429,GR-196,429,GR196429,GR196,429 | |
GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice. | |||
T70812 | PF-05236216 hydrochloride | ||
PF-05236216 hydrochloride is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice. | |||
T63375 | FT709 | ||
FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM). Among others, USP9X is associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization and circadia... | |||
T80849 | VU661 | ||
VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening. |